Studies on pattern regulation in hydra. II. Factors controlling hypostome formation.

Studies on pattern regulation in hydra II . Factors

In a previous paper (Webster & Wolpert, 1966 a) it was shown that during regulation the time required for the determination of the dominant region, the hypostome, was dependent on the original position of the hypostome-forming region on the linear axis. Hypostome determination occurred more quickly from distal than from proximal regions, suggesting an axial gradient. As Spiegelman (1945) has po...

Induction of secondary axis in hydra revisited: New insights into pattern formation

In 1909, several years before the famous `Organizer’ experiments of Spemann and Mangold, Ethel Browne demonstrated induction of a secondary axis in hydra by grafting a hypostome. Based on this and subsequent work, in the late sixties, Lewis Wolpert proposed the theory of morphogen gradients and positional information. We have studied secondary axis induction by hypostome and foot tissue using t...

Studies on pattern regulation in hydra

In a previous paper (Webster & Wolpert, 1966 a) it was shown that during regulation the time required for the determination of the dominant region, the hypostome, was dependent on the original position of the hypostome-forming region on the linear axis. Hypostome determination occurred more quickly from distal than from proximal regions, suggesting an axial gradient. As Spiegelman (1945) has po...

Nucleic acid and protein synthesis and pattern regulation in hydra. I. Regional patterns of synthesis and changes in synthesis during hypostome formation.

Hydra provides a convenient system for the study of the regulation of a linear pattern of organization. Almost any region is capable of being reconstituted into the whole organism and regulation is always polarized, i.e. distal structures (hypostome and tentacles) are formed from distal ends and proximal structures (peduncle and basal disk) from proximal ends. Two models have recently been prop...

Studies on pattern regulation in hydra. I. Regional differences in time required for hypostome determination.